After the sudden change in Dr. Loren’s behavior in the last issue of Think Tank I am glad that this one gives a good amount of background into why he is acting like this. Really, it comes down to his trust in Mirra was shattered and he is numb. The smartest guy around was tricked by one of the oldest scams in the book.
Because of that moment he has thrown himself into projects that are far beyond anything ethical, but with the premise that they are just a proof of concept. That he is not making actual functional biological weapons. Only he know full well that the results of his finding will lead to that and he is pushing it forward anyway.
Which still seems harsh even for Dr. Loren until you see how mean he is to Mirra. Then, you realize just how cold he can be. Still, he seems to be working with some agenda in mind. We get a glimpse of it in the very last page, but not enough to see where his plans are going. Hopefully his plan works out this time otherwise hes created what is probably the single worst weapon since the atomic bomb.